Methyl Ethyl Ketone (MEK)

Overview

Methyl Ethyl Ketone (MEK, CAS No: 78-93-3), also known as 2-butanone, is a colorless, volatile, and flammable liquid. This organic compound, belonging to the ketone family, has a sharp, sweet odor and is widely used as a powerful industrial solvent.

MEK is moderately soluble in water and miscible with most organic solvents. Its high solvency power and suitable evaporation rate make it a preferred choice in the paints, coatings, adhesives, and plastics industries. Industrial production is typically achieved through the dehydrogenation of secondary butanol or catalytic oxidation of n-butane, offering ≥99.5% purity.

Applications

Methyl Ethyl Ketone has a wide range of industrial and consumer applications:

Technical Specifications

Safety Information

Hazard Symbols and Statements

Flammable Eye and Skin Irritation Central Nervous System Effects

Personal Protective Equipment (PPE)

• Chemical-resistant gloves (nitrile or neoprene)
• Chemical safety goggles or face shield
• Respiratory protection with organic vapor filter
• Chemical-resistant apron or work clothing
• Adequate ventilation or local exhaust system

Storage Conditions

• Store in a cool, well-ventilated area
• Keep away from ignition sources and sparks
• Store separately from oxidizing agents and strong acids/bases
• Use stainless steel, glass, or suitable plastic (HDPE, PTFE) containers
• Storage temperature: 15-25°C

Fire Fighting Measures

• Suitable extinguishers: Dry chemical powder, CO₂, alcohol-resistant foam
• Avoid water jets, as they may spread the fire
• Intervene with appropriate protective equipment by trained personnel
• Evacuate area and call firefighters for large fires

Handling and Storage

Handling

• Ensure containers are tightly sealed during transport
• Label as "Flammable Liquid"
• Ground equipment to prevent static electricity buildup
• Avoid eating, drinking, or smoking during handling
• Use stainless steel containers for bulk transport

Storage

• Store in stainless steel, glass, or suitable plastic (HDPE, PTFE) containers
• Use explosion-proof electrical systems
• Ensure proper ventilation systems in storage tanks
• Keep fire extinguishing equipment in storage areas
• Prohibit smoking in storage areas

Spill Response Measures

• Remove all ignition sources
• Use chemical-resistant clothing and respiratory protection
• Absorb small spills with sand, vermiculite, or other absorbent materials
• Seek professional help for large spills
• Wash spill area with plenty of water

Regulatory Information

GHS Classification

• Flammable Liquid, Category 2
• Skin Irritation, Category 2
• Eye Irritation, Category 2A
• Specific Target Organ Toxicity (Single Exposure), Category 3

Key Regulations

• REACH: Registered
• CLP: Compliant
• OSHA: Subject to Hazard Communication Standard
• NFPA 704: Health 1, Flammability 3, Reactivity 0
• EPA: Classified as a VOC

International Regulations

• European Union: Subject to Directive 2008/58/EC
• USA: Listed on EPA TSCA inventory
• China: Listed on IECSC
• Japan: Listed on ISHL

Environmental Information

Environmental Impact

Methyl Ethyl Ketone rapidly degrades in the atmosphere through photochemical reactions (half-life: 1-3 days). It exhibits moderate toxicity to aquatic organisms when released into water sources. MEK is biodegradable and does not persist in the environment.

Biodegradation

• Air: Photochemical reactions, 1-3 days half-life
• Water: Degraded by microbial activity within 5-28 days
• Soil: Rapid degradation via microbial activity

Waste Management

• Classified as hazardous waste
• Small quantities can be evaporated in licensed facilities
• Large quantities must be incinerated in licensed hazardous waste facilities
• Dispose of in accordance with local regulations
• Prevent release into sewage systems

Frequently Asked Questions

How is Methyl Ethyl Ketone produced?

MEK is typically produced through the dehydrogenation of secondary butanol or catalytic oxidation of n-butane. Industrial-scale production uses continuous distillation processes.

What is the difference between Methyl Ethyl Ketone and acetone?

MEK (C₄H₈O) has a longer alkyl chain than acetone (C₃H₆O) and a higher boiling point. MEK is a stronger solvent and evaporates more slowly.

Does Methyl Ethyl Ketone damage plastics?

MEK can dissolve or deform polystyrene, PVC, and some plastics. Polyethylene and polypropylene are resistant to short-term exposure but should avoid prolonged contact.

What is the shelf life of Methyl Ethyl Ketone?

When stored in tightly sealed containers, MEK has a shelf life of approximately 2 years. It should be protected from moisture and stored airtight.

What should I do if MEK comes into contact with skin?

Wash with plenty of soap and water. Prolonged contact may cause dryness or irritation. If irritation persists, seek medical attention. In case of eye contact, rinse with water for at least 15 minutes and consult a doctor.